four. The influence of small-dose IL-2 and Treg adoptive mobile therapy in clients with sort 1 diabetic issues. 36. Treg cells-the following frontier of mobile remedy. 31. Adoptive Treg Cell Therapy in a Patient With Systemic Lupus Erythematosus. 38. Engineering a Single-Agent Cytokine/Antibody Fusion That Selectively Expands Regulatory T Cells for Autoimmune Disease Therapy. 5. Precision Engineering of an Anti-HLA-A2 Chimeric Antigen Receptor in Regulatory T Cells for Transplant Immune Tolerance. forty one. A human anti-IL-2 antibody that potentiates regulatory T cells by a composition-based system. fifteen. Functional CRISPR dissection of gene networks managing human regulatory T mobile identification. Cell Stem Cell. 2018 Jun 01 22(6):810-823. Sneddon JB, Tang Q, Stock P, Bluestone JA, Roy S, Desai T, Hebrok M. PMID: 29859172 PMCID: PMC6007036. J Immunol. 2018 10 01 201(7):2094-2106. Spangler JB, Trotta E, Tomala J, Peck A, Young TA, Savvides CS, Silveria S, Votavova P, Salafsky J, Pande VS, Kovar M, Bluestone JA, Garcia KC.
Cancer Immunol Res. 2018 twelve 6(12):1445-1452. Young A, Quandt Z, Bluestone JA. Diabetes. 2018 08 67(8):1471-1480. Stamatouli AM, Quandt Z, Perdigoto AL, Clark PL, Kluger H, Weiss SA, Gettinger S, Sznol M, Young A, Rushakoff R, Lee J, Bluestone JA, Anderson M, Herold KC. Immunity. 2019 02 19 50(2):362-377.e6. Van Gool F, Nguyen MLT, Mumbach MR, Satpathy AT, Rosenthal WL, Giacometti S, Le DT, Liu W, Brusko TM, Anderson MS, Rudensky AY, Marson A, Chang HY, Bluestone JA. Nature. 2020 06 582(7812):416-420. Cortez JT, Montauti E, Shifrut E, Gatchalian J, Zhang Y, Shaked O, Xu Y, Roth TL, Simeonov DR, Zhang Y, Chen S, Li Z, Woo JM, Ho J, Vogel IA, Prator GY, Zhang B, Lee Y, Sun Z, Ifergan I, Van Gool F, Hargreaves DC, Bluestone JA, Marson A, Fang D. PMID: 32499641 PMCID: PMC7305989. Cell. 2022 03 03 185(5):881-895.e20. Su Y, Yuan D, Chen DG, Ng RH, Wang K, Choi J, Li S, Hong S, Zhang R, Real-mom-Sex-tape Xie J, Kornilov SA, Scherler K, Pavlovitch-Bedzyk AJ, Dong S, Lausted C, Lee I, Fallen S, Dai CL, Baloni P, Smith B, Duvvuri VR, Anderson KG, Li J, Yang F, Duncombe CJ, McCulloch DJ, Rostomily C, Troisch P, Zhou J, Mackay S, DeGottardi Q, May DH, Taniguchi R, Gittelman RM, Klinger M, Snyder TM, Roper R, Wojciechowska G, Murray K, Edmark R, Evans S, Jones L, Zhou Y, Rowen L, Liu R, Chour W, Algren HA, Berrington WR, Wallick JA, Cochran RA, Micikas ME, ISB-Swedish COVID-19 Biobanking Unit, Wrin T, Petropoulos CJ, Cole HR, Fischer TD, Wei W, Hoon DSB, Price ND, Subramanian N, Hill JA, Hadlock J, Magis AT, Ribas A, Lanier LL, Boyd SD, Bluestone JA, Chu H, Hood L, Gottardo R, Greenberg PD, Davis MM, Goldman JD, Heath JR. PMID: 35216672 PMCID: PMC8786632.
Cell. 2020 12 ten 183(6):1479-1495.e20. Su Y, Chen D, Yuan D, Lausted C, Choi J, Dai CL, Voillet V, Duvvuri VR, Scherler K, Troisch P, Baloni P, Qin G, Smith B, Kornilov SA, Rostomily C, Xu A, Li J, Dong S, Rothchild A, Zhou J, Murray K, Edmark R, Hong S, Heath JE, Earls J, Zhang R, Xie J, Li S, Roper R, Jones L, Zhou Y, Rowen L, Liu R, Mackay S, O'Mahony DS, Dale CR, Wallick JA, Algren HA, Zager MA, ISB-Swedish COVID19 Biobanking Unit, Wei W, Price ND, Huang S, Subramanian N, Wang K, Magis AT, Hadlock JJ, Hood L, Aderem A, Bluestone JA, Lanier LL, Greenberg PD, Gottardo R, Davis MM, Goldman JD, Heath JR. PMID: 33171100 PMCID: PMC7598382. Front Immunol. 2021 12:686439. Muller YD, Ferreira LMR, Ronin E, Ho P, Nguyen V, Faleo G, Zhou Y, Lee K, Leung KK, Skartsis N, Kaul AM, Mulder A, Claas FHJ, Wells JA, Bluestone JA, Tang Q. PMID: 34616392 PMCID: PMC8488356.
Front Immunol. 2021 12:744763. Balcerek J, Shy BR, Putnam AL, Masiello LM, Lares A, Dekovic F, Acevedo L, Lee MR, Nguyen V, Liu W, Paruthiyil S, Xu J, Leinbach AS, Bluestone JA, Tang Q, Esensten JH. Front Med (Lausanne). 2018 5:351. Bridge JA, Lee JC, Daud A, Wells JW, Bluestone JA. Nat Med. 2018 07 24(7):1005-1014. Trotta E, Bessette PH, Silveria SL, Ely LK, Jude KM, Le DT, Holst CR, Coyle A, Potempa M, Lanier LL, Garcia KC, Crellin NK, Rondon IJ, Bluestone JA. Cell Metab. 2020 01 07 31(1):46-61. Warshauer JT, Bluestone JA, Anderson MS. PMID: 31839487 PMCID: PMC6986815. 3. Polyclonal Regulatory T Cell Manufacturing Under cGMP: A Decade of Experience. Cancer-introduced microvesicles, encompassing exosome, apoptotic bodies, and microparticles, are compact mobile membrane-derived vesicles expressing mobile proteins at their surface and that contains DNA, RNA, miRNA and proteins, and smaller molecules of the cell of origin. Seven of the users are elected by a committee of the Italian Parliament.