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Current Opinion in Pediatrics. Expert Opinion on Drug Delivery. This smoother expertise of nicotine delivery into the physique makes nicotine salts standard amongst those new to vaping Vape E-Liquids and those in search of a nicotine replacement therapy that's extra commensurate to smoking conventional cigarettes. 2021) ‘Effect of Exposure to e-Cigarettes With Salt vs Free-Base Nicotine on the Appeal and Sensory Experience of Vaping: A Randomized Clinical Trial’, JAMA network open, 4(1), pp

>Pod mods, nonetheless, can present high levels of nicotine with out the destructive smoking experience. In June 2015, Juul introduced a pod mod device containing nicotine salt. Tested show that the pod mods Juul, Bo, Phix, and Suorin contain nicotine salts in an answer with propylene glycol and glycerin. A free-base nicotine answer with an acid reduces the pH, which makes it potential to offer higher ranges of nicotine without irritating the throat

>During July-September 2019, doable cases of lung harm associated with e-cigarette use in Illinois and Wisconsin were investigated to find out signs, exposures, and medical care history related to the outbreak. In July 2019, the Illinois Department of Public Well being and the Wisconsin Division of Health Services launched a coordinated epidemiologic investigation after receiving reviews of a number of instances of lung damage in previously healthy individuals who reported digital cigarette (e-cigarette) use, Vape Kits or vaping (1)

>This report describes options of e-cigarette product use by patients in Illinois and Wisconsin. Within this category of vaping gadgets, vape devices some had been closed-pod programs (also referred to as "mods") designed to be used with proprietary nicotine-containing products (e.g., JUUL); nonetheless, most were common "Vape Devices pens" which can be adaptable to the prefilled THC cartridges reported by many patients

> In contrast, 77% of nicotine-containing products have been bought as prefilled cartridges, and 83% were obtained from industrial distributors. Among the 86 interviewed patients, 75 (87%) reported using e-cigarette merchandise containing THC, the principal psychoactive element of cannabis, during the 3 months previous sickness; Sixty one (71%) reported utilizing nicotine-containing merchandise; 50 (58%) reported using both THC- and nicotine-containing merchandise

> Overall, Vape Kits 75 (87%) of 86 interviewed patients reported utilizing e-cigarette products containing tetrahydrocannabinol (THC), and sixty one (71%) reported utilizing nicotine-containing merchandise. As of 2023, many manufacturers in the United Kingdom have been observed to have shifted to nicotine salt-solely disposable pods, after beforehand vape store offering a majority of products in typical liquids containing freebase nicotine.

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