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Henkel T, Brunne RM, Müller H (1999) Statistical investigation into the structural complementarity of all-natural solutions and artificial compounds. Gaisser S, Kellenberger L, Kaja AL, Weston AJ, Lill RE, Wirtz G, Kendrew SG, Low L, Sheridan RM, Wilkinson B, Galloway IS, Stutzman-Engwall K, McArthur HA, Staunton J, Leadlay PF (2003) Direct manufacturing of ivermectin-like medications soon after area exchange in the avermectin polyketide synthase of Streptomyces avermitilis ATCC31272. Gaisser S, Reather J, Wirtz G, Kellenberger L, Staunton J, Leadlay PF (2000) A defined system for hybrid macrolide biosynthesis in Saccharopolyspora erythraea. Cropp TA, Wilson DJ, Reynolds KA (2000) Identification of a cyclohexylcarbonyl CoA biosynthetic gene cluster and software in the output of doramectin. Decker H, Haag S (1995) Cloning and characterization of a polyketide synthase gene from Streptomyces fradiae Tü2717, which carries the genes for biosynthesis of the angucycline antibiotic urdamycin A and a gene likely concerned in its oxygenation. Bate N, Cundliffe E (1999) The mycinose-biosynthetic genes of Streptomyces fradiae, producer of tylosin. Khosla C, Gokhale R, Jacobsen JR, Cane DE (1999) Tolerance and specificity of polyketide synthases. Del Vecchio F, Petkovic H, Kendrew SG, Low L, Wilkinson B, Lill R, Cortes J, Rudd BA, Staunton J, Leadlay PF (2003) Active-internet site residue, domain and module swaps in modular polyketide synthases.
Donadio S, Sosio M (2003) Strategies for combinatorial biosynthesis with modular polyketide synthases. Jacobsen JR, Hutchinson CR, Cane DE, Khosla C (1997) Precursor directed biosynthesis of novel erythromycin analogs by an engineered polyketide synthase. Frykman S, Leaf T, Carreras C, Licari P (2001) Precursor-directed generation of erythromycin analogs by Saccharopolyspora erythraea. Chung L, Liu L, Patel S, Carney JR, Reeves CD (2001) Deletion of rap-QONML from the rapamycin gene cluster of Streptomyces hygroscopicus gives output of the 16-O-desmethyl-27-desmethoxy analog. Inouye M, Takada Y, Muto N, Beppu T, Horinouchi S (1994) Characterization and expression of a P-450-like mycinamicin biosynthesis gene utilizing a novel Micromonospora-Escherichia coli shuttle cosmid vector. Recent experiments have located comparable prices of crossover (referred to as polymorphism) using official records coupled with therapy and evaluation data files. 27, has been making use of cam web sites for two yrs. Hopwood DA (1999) Forty a long time of genetics with Streptomyces: from in vivo by means of in vitro to in silico.
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