Within the pharmaceutical industry, obesity is now viewed as the "trillion dollar disease". That's the estimated amount of earnings a successful weight loss drug can expect to make. But are organizations getting close to delivering a diet pill that truly works - meaning, a pill that's both effective and safe at dealing with obesity? The solution, it seems, is No.
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It is true that the Food and Drug Administration (FDA) has endorsed a tiny number of weight loss pills as Meridia and Xenical for long lasting use in the therapy of obesity (BMI > thirty). But evidence built up in clinical trials suggests the effectiveness of these obesity medications is under impressive. Total yearly weight reduction tends to experience the number 8-20 pounds. Furthermore, the highest fat loss is likely to be reached by patients who take part in supervised trials including a combination of drug treatment, diet, counseling and exercise. Which makes it difficult to find out the highly accurate result of the medication itself. By comparison, less well supervised obesity drug trials generally have an improved drop-out price and reduced weight loss. Plus the longer the trial, the lower the compliance and also the lower the fat reduction. In short, while beneficial to some patients, weight loss drugs aren't yet the answer to weight problems, particularly when elements like cost are taken into consideration.
Might we be surprised? Not really. After all, even bariatric surgical treatment is no guarantee of long lasting weight loss unless patients comply with the necessary post operative dietary regimen. In fact, some obesity consultants say that healthcare interventions like drugs as well as surgery are practically by definition doomed to failure, because the simple reason that they take responsibility and control away from patients. According to this view, it is only when patients accept full responsibility for their eating habits and lifestyle, that they've an actual chance of achieving a normal weight in the long term.
The fact is that, this view satisfies no one! It doesn't satisfy the pharmaceutical companies, who have to earn a living. It does not satisfy doctors, who need to give hope to their
overweight patients, and it does not satisfy consumers who want instant weight loss without having to change the eating habits of theirs. In a nutshell, there is an overwhelming need for an obesity pill, but a viable product has yet to present themselves.
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Demand for diet pills isn't restricted to those suffering from clinical obesity. Millions of consumers with under 40 pounds to lose take non
prescription pills to burn off unwanted fat or increase their speed of weight loss. Based on research conducted by the University of Michigan, about twenty five % of woman pupils turn to anorectic weight loss supplements when they are attempting to slim down, which includes laxatives and diuretics.
These non prescription pills are harder to assess, as they are not at the mercy of the same high level of regulation as prescription only drugs. So only some ingredients have being examined, other labeling requirements and dosages are less stringent, and reporting of "adverse health or events" problems is not necessary. In addition, couple of long-term clinical trials are performed on non prescription pills, so challenging proof concerning the safety of theirs and efficacy is scarce. Meantime, the massive profits to be made out of these weight loss products would mean they can be supported by expensive marketing promotions to increase consumer acceptance, making regulation and control much more of an uphill fight. Certainly, the FDA has found it extremely difficult to ban over-the-counter diet pills, even after reports of illness as well as injury.
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