Vitamin B6 occurs in three forms--pyridoxine, pyridoxal, and pyridoxamine. B6 is absorbed in the large intestine. The muscle shops approximately 75 80 % of the vitamin although the living stores approximately 5-10 %.
B6 is required for transaminations, decarboxylations, alpilean weight loss reviews (
Suggested Looking at) dehydratases, side chain cleavage reactions, and ammonia release. Its aldehyde group functions as a Schiff base to act in response with the amino groups of amino acids. It essentially acts to shuttle nitrogen among compounds.
Functions- The three forms of B6 could all be converted to the coenzyme PLP which aids in transamination and protein metabolism. PLP is vital for glycogen degradation; it also helps with the development of the neurotransmitter, serotonin, the nonprotein portion of hemoglobin (heme), nucleic acids, and lecithin. Vitamin B6 is essential for the metabolism of
tryptophan to niacin.
Overall Reactions:
· Transaminations These reactions are needed to reuse as well as reuse nitrogen within the body. They're the initial phase in amino acid catabolism and the very last phase in the synthesis of nonessential amino acids. Example: a-ketoglutarate + asparate glutamate + oxaloacetate
· Serine/
Threonine Deamination (Dehydratases) This response has the generation of the a-keto acids of serine and threonine through oxidative removal of N as ammonia Example: Serine a-keto-serine + NH4+
· Decarboxylation These reactions often occur on the neuroactive amines of seratonin, tyramine, histamine, and GABA. They also are important in porphyrin synthesis, intermediates in the synthesis of sphingomyelin, lecithin and taurine, and for the breakdown as well as desulfuration of cysteine.
· Glycogen Phosphorylase fifty % of all B6 in the body is sure to glycogen phosphorylase however, the value is unknown. The reaction is vital for recycling of folate and it is as follows: