Vitamin B6 occurs in three forms--pyridoxine, pyridoxal, and pyridoxamine. B6 is absorbed in the large intestine. The muscle shops approximately 75-80 % of the vitamin even though the live shops approximately 5 10 %.
B6 is recommended for transaminations, ammonia release,, side-chain cleavage reactions, dehydratases and decarboxylations. Its aldehyde group acts as a Schiff base to react with the amino groups of amino acids. It essentially acts to shuttle nitrogen among compounds.
Functions- The 3 forms of B6 could all be converted on the coenzyme PLP which aids in transamination and protein metabolism. PLP is vital for glycogen degradation; it may also help with the formation of the neurotransmitter, serotonin, the nonprotein portion of
hemoglobin (heme), nucleic acids, and lecithin. Vitamin B6 is essential for the metabolism of tryptophan to niacin.
Overall Reactions:
· Transaminations These reactions are necessary to recycle and reuse nitrogen in the body. They're the first stage in amino acid catabolism and also the very last phase in the synthesis of nonessential amino acids. Example: a-ketoglutarate + asparate glutamate + oxaloacetate
· Serine/ Threonine Deamination (Dehydratases) This response offers the production of the a keto acids of serine as well as threonine through oxidative removal of N as ammonia Example: Serine a-keto-serine + NH4+
· Decarboxylation These reactions often occur on the neuroactive amines of seratonin, tyramine, histamine, and GABA. Additionally they are critical in porphyrin synthesis, intermediates in the synthesis of sphingomyelin, taurine and lecithin, and for the description and desulfuration of cysteine.
· Glycogen Phosphorylase 50 % of all B6 in the body is likely to glycogen phosphorylase however, the value is unknown. The reaction is crucial for recycling of folate and alpilean reviews real (
startup.info) it is as follows: