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With respect to food, preclinical research steered that prime doses of the opiate antagonist naloxone elevated sugar consumption and opiate-like withdrawal signs-together with elevated plus maze anxiety, teeth chattering, and head shakes-in sugar-binging rats following a period of abstinence.150-152 These results were not replicated amongst rats on high-fats diets.153 The efficacy of opioid antagonists like naltrexone in treating food addiction has yet to be explored in human subjects but deserves research attention.

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Disclosures. Dr Potenza studies that he has no conflicts of interest over the past 3 years to report as associated to the topic of the report. Dr Potenza has acquired financial assist or compensation for the next: Dr Potenza consults for and is an advisor to Boehringer Ingelheim; has consulted for and has financial interests in Somaxon; has received research assist from the National Institutes of Health, Veteran's Administration, Mohegan Sun, and Forest Laboratories, Ortho-McNeil and Oy-Management/Biotie pharmaceuticals; has participated in surveys, mailings or telephone consultations related to drug addiction, ICDs or different health subjects; has consulted for regulation workplaces and the Federal Public Defender's Office in points associated to ICDs; has carried out grant critiques for ギャンブル依存症 対策 the National Institutes of Health and other agencies; has given tutorial lectures in grand rounds, Persevering with Medical Education events and different clinical or scientific venues; has generated books or e-book chapters for publishers of psychological well being texts; and offers clinical care within the Connecticut Department of Mental Health and Addiction Services Drawback Playing Providers Programme.

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